Immunonephelometry and Reverse Hybrydization Genotyping in Diagnosis of Alpha-1-Antitrypsin Deficiency in Macedonians

نویسندگان

  • Olivija Efinska-Mladenovska
  • Dejan Trajkov
  • Aleksandar Petlichkovski
  • Olgica Sibinovska
  • Slavica Hristomanova Mitkovska
  • Mirko Spiroski
چکیده

MATERIAL AND METHODS: At the Institute of Immunobiology and Human Genetics, part of the Faculty of Medicine in Skopje, in the previous 7 years, total of 361 patients with suspected alpha-1-antitrypsin (AAT) deficiency were referred for analysis of AAT concentration using nephelometry (Dade Behring) and subsequent AAT genotyping of individuals with alpha-1antytripsin deficiency at protein level, based on reverse hybridization technique.

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تاریخ انتشار 2015